Heme Oxygenase-1-IN-3
Heme Oxygenase-1-IN-3 (compound 4) is a highly selective heme oxygenase-1 (HO-1) inhibitor (Kd=141 nM) that can be used in the research of cancer and neurodegenerative diseases[1].
Product Specifications
CAS Number
[1043712-39-5]
UNSPSC
12352101
Target
Heme Oxygenase (HO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/heme-oxygenase-1-in-3.html
Smiles
O=S(NCCNC1=NC(C2=CC(Br)=CC=C2)=NC3=CC=CC=C31)(C4=CC=C(F)C=C4)=O
Molecular Formula
C22H18BrFN4O2S
Molecular Weight
501.37
References & Citations
[1]Shuai Han, et al. Highly Selective Novel Heme Oxygenase-1 Hits Found by DNA-Encoded Library Machine Learning beyond the DEL Chemical Space. ACS Medicinal Chemistry Letters (2024) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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