H3K27 (Me2) (15-34)
H3K27 (Me2) (15-34), a histone peptide, is a repressive chromatin mark derived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27 (Me) [1][2].
Product Specifications
UNSPSC
12352209
Target
Histone Demethylase
Type
Peptides
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/h3k27-me2-15-34.html
Solubility
10 mM in DMSO
Smiles
CN(CCCC[C@H](NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](C)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H]1N(C([C@H](C)N)=O)CCC1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CO)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(NCC(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)C
Molecular Formula
C86H154N30O25
Molecular Weight
2008.36
References & Citations
[1]Elizabeth T Wiles, et al. H3K27 Methylation: A Promiscuous Repressive Chromatin Mark. Curr Opin Genet Dev. 2017 Apr;43:31-37.|[2]Brian P Chadwick, et al. Multiple Spatially Distinct Types of Facultative Heterochromatin on the Human Inactive X Chromosome. Proc Natl Acad Sci U S A. 2004 Dec 14;101 (50) :17450-5.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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