Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Werner syndrome RecQ helicase-IN-3

Werner syndrome RecQ helicase-IN-3 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC50 value of 0.06 µM. Werner syndrome RecQ helicase-IN-3 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-3 shows anticancer activity[1].

Product Specifications

CAS Number

2869954-98-1

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/werner-syndrome-recq-helicase-in-3.html

Purity

99.94

Solubility

DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(N1CCN(CC1)C2=C(CC)N(CC(NC3=CC=C(C(F)(F)F)C=C3Cl)=O)C4=NC(C5=CCOCC5)=NN4C2=O)C6=NC=CC=C6O

Molecular Formula

C31H30ClF3N8O5

Molecular Weight

687.07

References & Citations

[1]Vincent Bordas, et al. Triazolo-pyrimidine analogues for treating diseases connected to the inhibiton of werner syndrome recq helicase (wrn) . WO2022249060A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-PIP (PIP1;1, PIP1;2, PIP1;3, PIP1;4, PIP1;5) aquaporins, DyLight® 650 conjugated (40 µg)
AS09 487-DL650 40 µg

Anti-PIP (PIP1;1, PIP1;2, PIP1;3, PIP1;4, PIP1;5) aquaporins, DyLight® 650 conjugated (40 µg)

Sign In for Pricing
View Details
Uncoated Mouse CCL12/MCP-5 (Monocyte Chemotactic Protein 5) ELISA Kit
E-UNEL-M0041-01 5x 96 Tests

Uncoated Mouse CCL12/MCP-5 (Monocyte Chemotactic Protein 5) ELISA Kit

Sign In for Pricing
View Details
Uncoated Mouse CCL12/MCP-5 (Monocyte Chemotactic Protein 5) ELISA Kit
E-UNEL-M0041-02 15x 96 Tests

Uncoated Mouse CCL12/MCP-5 (Monocyte Chemotactic Protein 5) ELISA Kit

Sign In for Pricing
View Details
GranULin (GRN) Human Gene Knockout Kit (CRISPR)
KN202139 1 Kit

GranULin (GRN) Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Colloidal Gold Conjugated Goat Affinity Purified Antibody to Mouse Immunoglobulins,  30nm
GAF-447-30 1 mL

Colloidal Gold Conjugated Goat Affinity Purified Antibody to Mouse Immunoglobulins, 30nm

Sign In for Pricing
View Details
Bulk Human IgG4 (IB4) Isotype Control SPLEPG
ICH2257SPLEPG-1mg 1 mg

Bulk Human IgG4 (IB4) Isotype Control SPLEPG

Sign In for Pricing
View Details