Bacoside A3

Bacoside A3 is a triterpenoid saponin isolated from Bacopa monnieri. Bacoside A3 has neuroprotective activity, downregulating β-amyloid-induced inflammatory responses and inhibiting neuronal apoptosis. Bacoside A3 can be used in the study of Alzheimer's disease[1][2].

Product Specifications

CAS Number

[157408-08-7]

UNSPSC

12352005

Hazard Statement

H301+H311+H331

Target

Apoptosis; COX; NO Synthase

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bacoside-a3.html

Purity

99.85

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@]12[C@@]34[C@@](CC[C@]1([H])[C@@]5([C@@](C(C)([C@@H](O[C@@]6([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O6)O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)CO)O[C@]8([H])O[C@@H](CO)[C@H](O)[C@H]8O)CC5)C)([H])CC2)C)([H])[C@]9([H])[C@@](OC4)(O[C@@H](/C=C(C)/C)C[C@@]9(O)C)C3

Molecular Formula

C47H76O18

Molecular Weight

929.10

Precautions

H301+H311+H331

References & Citations

[1]Vini C Sekhar, et al. Insights Into the Molecular Aspects of Neuroprotective Bacoside A and Bacopaside I. Curr Neuropharmacol. 2019;17 (5) :438-446.|[2]Bai Q, et al. Isolation and neuronal apoptosis inhibitory property of bacoside‐A3 via downregulation of β‐amyloid induced inflammatory response[J]. Biotechnology and applied biochemistry, 2022, 69 (2) : 726-734.