Curindolizine
Product Specifications
UNSPSC Description
Curindolizine, indolizine alkaloid , displays an anti-inflammatory action in lipopolyssacharide (LPS)-induced RAW 264.7 macrophages with an IC50 value of 5.31 μM[1].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/curindolizine.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]([C@@]1(C=C2)[C@](C(N3[C@@H]4C)=CC([C@](C=CC5=CC=C6C)([H])[C@H](N56)C)=C3C)([H])[C@@](N7C2=CC=C7C)([H])[C@@H]4O1)O
Molecular Weight
469.62
References & Citations
[1]Wen Bo Han,et al. Curindolizine, an Anti-Inflammatory Agent Assembled via Michael Addition of Pyrrole Alkaloids Inside Fungal Cells. Org Lett. 2016 Apr 15;18(8):1816-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N10297/Curindolizine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N10297/
Clinical Information
No Development Reported
CAS Number
1899935-44-4
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