Curindolizine

Curindolizine, indolizine alkaloid , displays an anti-inflammatory action in lipopolyssacharide (LPS) -induced RAW 264.7 macrophages with an IC50 value of 5.31 μM[1].

Product Specifications

CAS Number

[1899935-44-4]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/curindolizine.html

Solubility

10 mM in DMSO

Smiles

C[C@@H]([C@@]1(C=C2)[C@](C(N3[C@@H]4C)=CC([C@](C=CC5=CC=C6C)([H])[C@H](N56)C)=C3C)([H])[C@@](N7C2=CC=C7C)([H])[C@@H]4O1)O

Molecular Formula

C30H35N3O2

Molecular Weight

469.62

References & Citations

[1]Wen Bo Han, et al. Curindolizine, an Anti-Inflammatory Agent Assembled via Michael Addition of Pyrrole Alkaloids Inside Fungal Cells. Org Lett. 2016 Apr 15;18 (8) :1816-9.