Guaijaverin
Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities[1][2][3].
Product Specifications
CAS Number
[22255-13-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/guaijaverin.html
Purity
99.79
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(O[C@H]2[C@@H]([C@H]([C@H](CO2)O)O)O)=C(C3=CC=C(O)C(O)=C3)OC4=CC(O)=CC(O)=C14
Molecular Formula
C20H18O11
Molecular Weight
434.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Shabana S, et al. Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava. Biosci Biotechnol Biochem. 2010;74 (4) :878-80.|[2]Caruso IP, et al. Exploring the binding mechanism of Guaijaverin to human serum albumin: fluorescencespectroscopy and computational approach. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Nov;97:449-55.|[3]Prabu GR, et al. Guaijaverin -- a plant flavonoid as potential antiplaque agent against Streptococcus mutans. J Appl Microbiol. 2006 Aug;101 (2) :487-95.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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