(R) -5,7-Dimethoxyflavanone

(R) -5,7-Dimethoxyflavanone shows potent antimutagenic activity against MeIQ mutagenesis in Ames test using the S. typhimurium TA100 and TA98 strains[1]. And (R) -5,7-Dimethoxyflavanone significantly and dose-dependently inhibits the inflammatory mediato[1].

Product Specifications

CAS Number

[1277188-85-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

TNF Receptor

Type

Natural Products

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/r-5-7-dimethoxyflavanone.html

Purity

99.98

Solubility

10 mM in DMSO

Smiles

O=C1C[C@H](C2=CC=CC=C2)OC3=CC(OC)=CC(OC)=C13

Molecular Formula

C17H16O4

Molecular Weight

284.31

Precautions

H302, H315, H319, H335

References & Citations

[1]Okuno Y, Marumoto S, Miyazawa M. Antimutagenic activity of flavonoids from Sozuku. Nat Prod Res. 2019;33 (6) :862-865.|[2]Rao YK, Fang SH, Tzeng YM. Anti-inflammatory activities of flavonoids isolated from Caesalpinia pulcherrima. J Ethnopharmacol. 2005;100 (3) :249-253.