GX-201
GX-201 is a selective NaV1.7 inhibitor, with an IC50 of V1.7[1].
Product Specifications
CAS Number
[1788071-27-1]
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gx-201.html
Purity
98.89
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(C1=C(F)C=C(OCC2CCN(CC2)CC3=CC(C(F)(F)F)=CC=C3Cl)C(C4CC4)=C1)NS(=O)(C)=O
Molecular Formula
C25H27ClF4N2O4S
Molecular Weight
563.00
References & Citations
[1]Girish Bankar, et al. Selective Na V 1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain. Cell Rep. 2018 Sep 18;24 (12) :3133-3145.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Nav1.7
Available Sizes
Curated Selection
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