EGFR-IN-124
EGFR-IN-124 (compound 10A) is an EGFR inhibitor, with IC50 of 0.54 μM. EGFR-IN-124 can be used in anti-cancer research[1].
Product Specifications
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-124.html
Smiles
O=C1C2(C3=C(C=CC=C3)N1)C4=C(N(C5=CC=CC=C5)N=C4C6=CNC7=C6C=CC=C7)NC(C8=CC=CC=C8)=C2C#N
Molecular Formula
C34H22N6O
Molecular Weight
530.58
References & Citations
[1]Eldehna WM, et al. Unveiling the anticancer potential of novel spirooxindole-tethered pyrazolopyridine derivatives. Bioorg Chem. 2024 Aug 31;153:107778.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1
Curated Selection
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