ZINC09518833
ZINC09518833 is a α-ketoamide nonpeptidic proteasome inhibitor with an IC50 value of 12.4 μM. ZINC09518833 binds both primed and nonprimed sites of the proteasome. ZINC09518833 is promising for research of multiple myeloma (MM) [1].
Product Specifications
CAS Number
893983-51-2
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zinc09518833.html
Smiles
O=C(C(C1=CN(CC(N(CC)CC)=O)C2=C1C=CC=C2)=O)NC3=CC=C4C(OCCO4)=C3
Molecular Formula
C24H25N3O5
Molecular Weight
435.47
References & Citations
[1]Zhou J, et al. Discovery of Novel Nonpeptidic Proteasome Inhibitors Using Covalent Virtual Screening and Biological Evaluation[J]. ACS Medicinal Chemistry Letters, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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