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Salusin-α

Salusin-α is an endogenous bioactive peptide with hemodynamic and cell proliferation activities. Salusin-α can stimulate the proliferation of quiescent vascular smooth muscle cells (VSMCs) and fibroblasts, leading to a rapid and significant decrease in blood pressure and heart rate, but its effect is weaker than that of Salusin-β. Salusin-α has potential application value in cardiovascular disease research[1].

Product Specifications

CAS Number

624735-22-4

UNSPSC

12352209

Target

Endogenous Metabolite

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/salusin-α.html

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N[C@@H](C)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N4[C@@H](CCC4)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(NCC(N5[C@@H](CCC5)C(N[C@@H](C)C(NCC(N6[C@@H](CCC6)C(NCC(N[C@@H](C)C(N[C@H](C(N)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]7N(CCC7)C([C@H](CC(C)C)NC([C@H](C)NC(CNC([C@@H](N)CO)=O)=O)=O)=O

Molecular Formula

C114H192N40O30

Molecular Weight

2602.99

References & Citations

[1]Shichiri, et al. "Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities." Nature medicine 9.9 (2003) : 1166-1172.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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