Insulin II (Rat, Mouse)

<strong>Insulin II (Rat, Mouse)</strong>_x000D_ <strong>Catalog number:</strong> MDP0852_x000D_ <strong>CAS Number: </strong>845730-65-6_x000D_ <strong>Sequence: </strong>A-chain: Gly-Ile-Val-Asp-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn B-chain:Phe-Val-Lys-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Met-Ser (Disulfide bonds between CysA6-CysA11, CysA7-CysB7, and CysA20-CysB19)_x000D_ <strong>Amount:</strong> 50 ug_x000D_ <strong>Molecular Weight:</strong> 5796.4 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals._x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Debès C, Papadakis A, Grönke S, Karalay Ö, Tain LS, Mizi A, Nakamura S, Hahn O, Weigelt C, Josipovic N, Zirkel A, Brusius I, Sofiadis K, Lamprousi M, Lu YX, Huang W, Esmaillie R, Kubacki T, Späth MR, Schermer B, Benzing T, Müller RU, Antebi A, Partridge L, Papantonis A, Beyer A. Ageing-associated changes in transcriptional elongation influence longevity Nature. 2023 Apr;616(7958):814-821._x000D_ 2: Chen H, Zhou W, Ruan Y, Yang L, Xu N, Chen R, Yang R, Sun J, Zhang Z. Reversal of angiotensin ll-induced β-cell dedifferentiation via inhibition of NF-κb signaling Mol Med. 2018 Aug 14;24(1):43._x000D_ 3: Wentworth BM, Rhodes C, Schnetzler B, Gross DJ, Halban PA, Villa-Komaroff L. The ratio of mouse insulin I:insulin II does not reflect that of the corresponding preproinsulin mRNAs Mol Cell Endocrinol. 1992 Aug;86(3):177-86._x000D_ 4: Verland S, Gammeltoft S. Functional receptors for insulin-like growth factors I and II in rat thymocytes and mouse thymoma cells Mol Cell Endocrinol. 1989 Dec;67(2-3):207-16._x000D_ 5: Wolf G, Hessabi B, Karkour A, Henrion U, Dahlhaus M, Ostmann A, Giese B, Fraunholz M, Grabarczyk P, Jack R, Walther R. The activation of the rat insulin gene II by BETA2 and PDX-1 in rat insulinoma cells is repressed by Pax6 Mol Endocrinol. 2010 Dec;24(12):2331-42._x000D_ 6: Horiuchi M, Mogi M, Iwai M. Signaling crosstalk angiotensin II receptor subtypes and insulin Endocr J. 2006 Feb;53(1):1-5._x000D_ 7: Holthuizen PE, Cleutjens CB, Veenstra GJ, van der Lee FM, Koonen-Reemst AM, Sussenbach JS. Differential expression of the human, mouse and rat IGF-II genes Regul Pept. 1993 Oct 20;48(1-2):77-89._x000D_ 8: Giddings SJ, Carnaghi LR, Fischer LJ, Miller CP. Differential regulation of rat insulin I and II messenger RNA synthesis: effects of fasting and cyproheptadine Mol Endocrinol. 1991 Apr;5(4):549-54._x000D_ 9: Pedone PV, Cosma MP, Ungaro P, Colantuoni V, Bruni CB, Zarrilli R, Riccio A. Parental imprinting of rat insulin-like growth factor II gene promoters is coordinately regulated J Biol Chem. 1994 Sep 30;269(39):23970-5._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15701644">10: Iwakura H, Hosoda K, Son C, Fujikura J, Tomita T, Noguchi M, Ariyasu H, Takaya K, Masuzaki H, Ogawa Y, Hayashi T, Inoue G, Akamizu T, Hosoda H, Kojima M, Itoh H, Toyokuni S, Kangawa K, Nakao K. Analysis of rat insulin II promoter-ghrelin transgenic mice and rat glucagon promoter-ghrelin transgenic mice J Biol Chem. 2005 Apr 15;280(15):15247-56. </a>_x000D_ _x000D_ <strong>Products Related to Insulin II (Rat, Mouse) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>