6α-Fluoroprednisolone

6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research[1][2][3].

Product Specifications

CAS Number

[53-34-9]

Product Name Alternative

Fluprednisolone

UNSPSC

12352211

Hazard Statement

H315, H319, H320

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/6α-fluoroprednisolone.html

Purity

95.93

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

C[C@]1(C2)[C@](CC[C@@](O)1C(CO)=O)([H])[C@@](C[C@@H]3F)([H])[C@@]([C@H]2O)([H])[C@](C3=CC4=O)(C=C4)C

Molecular Formula

C21H27FO5

Molecular Weight

378.43

Precautions

H315, H319, H320

References & Citations

[1]Schmidt KS, et al. In-house validation and factorial effect analysis of a liquid chromatography-tandem mass spectrometry method for the determination of corticosteroids in bovine and porcine muscle tissue. Anal Bioanal Chem. 2013 Jul;405 (19) :6287-97.|[2]Laron Z, et al. The comparative effect of 6 alpha-fluoroprednisolone, 6 alpha-methylprednisolone, and hydrocortisone on linear growth of children with congenital adrenal virilism and Addison's disease. J Pediatr. 1968 Nov;73 (5) :774-82. |[3]COLLINS EJ, et al. Influence of adrenal steroids on radio-calcium metabolism in young beagle dogs. Acta Endocrinol (Copenh) . 1963 Mar;42:348-54.