Cefquinome (sulfate)

Cefquinome sulfate is a broad-spectrum cephem antibiotic that has inhibitory effects on a variety of Gram-positive and Gram-negative bacteria, including Staphylococci, Streptococci, Pseudomonas, and Enterobacteriaceae[1][2][3].

Product Specifications

CAS Number

[118443-89-3]

UNSPSC

12352005

Hazard Statement

H315-H319-H334-H335-H410

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cefquinome-sulfate.html

Purity

98.63

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic)

Smiles

O=C1[C@@H](NC(/C(C2=CSC(N)=N2)=N\OC)=O)[C@@]3([H])SCC(C[N+]4=C5CCCCC5=CC=C4)=C(C(O)=O)N13.O=S(O)([O-])=O

Molecular Formula

C23H26N6O9S3

Molecular Weight

626.68

Precautions

P261-P264-P271-P273-P280-P284-P302+P352-P304+P340-P305+P351+P338-P362+P364-P391-P403+P233-P405-P501

References & Citations

[1]Chin NX, et al. In vitro activity of cefquinome, a new cephalosporin, compared with other cephalosporin antibiotics. Diagn Microbiol Infect Dis. 1992 May-Jun;15 (4) :331-7.|[2]Qu S, et al., Cefquinome-loaded microsphere formulations against Klebsiella pneumonia infection during experimental infections. Drug Deliv. 2018 Nov;25 (1) :909-915.|[3]Limbert M, et al., Antibacterial activities in vitro and in vivo and pharmacokinetics of cefquinome (HR 111V), a new broad-spectrum cephalosporin. Antimicrob Agents Chemother. 1991 Jan;35 (1) :14-9.