(S, R, S) -AHPC-PEG2-NH2 (dihydrochloride)
(S, R, S) -AHPC-PEG2-NH2 dihydrochloride (VH032-PEG2-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S, R, S) -AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[2341796-76-5]
Product Name Alternative
VH032-PEG2-NH2 (dihydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-peg2-nh2-dihydrochloride.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.Cl.Cl
Molecular Formula
C28H43Cl2N5O6S
Molecular Weight
648.64
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
Available Sizes
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