SN05

SN05 is a potent amino acid transport (AAT) inhibitor with Ki values of 2.77 μM, 0.73 μM, 0.87 μM, 3.7 μM, 7.25 μM, 7.23 μM and 2.22 μM for hASCT1, rASCT2, hASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively. SN05 can be used in the study of cancer[1].

Product Specifications

CAS Number

[2768663-51-8]

UNSPSC

12352005

Target

ASCT; EAAT

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sn05.html

Concentration

10mM

Purity

98.37

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC([C@@H](NC1)C[C@@H]1OC(C2=CC=C(C3=CC=CC=C3)C=C2)=O)=O

Molecular Formula

C18H17NO4

Molecular Weight

311.33

References & Citations

[1]Christof GREWER, et al. Inhibitors of amino acid transport. WO2022087630A1. 2022-04-28.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ASCT2; EAAT1; EAAT2; EAAT3; EAAT5

Available Sizes

Curated Selection

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