IL-18R alpha, Mouse (HEK293, His-Fc)
Selected Variant
HY-P75846
Size: 1 Each
IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines[1]. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ[2]. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18[3]. IL-18R alpha Protein, Mouse (HEK293, His-Fc) is a recombinant protein with a His-Fc label and is produced by HEK293 cells.
Product Specifications
Product Name Alternative
IL-18R alpha Protein, Mouse (HEK293, His-Fc), Mouse, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/il-18r-alpha-protein-mouse-hek293-his-fc.html
Molecular Formula
16182 (Gene_ID) Q61098 (K20-G326) (Accession)
Molecular Weight
Approximately 95-105 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
References & Citations
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
Price
Frequently Asked Questions
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