Anti-Hu CD187 FITC
CD187 (CXCR7) is a member of chemokine receptor family, but with discussed specificity. It is expressed in various tissues and cells, such as placenta, urinary bladder, fetal liver cells, tumor cells, activated endothelium, monocytes, lymphocytes, mature dendritic cells, and other.
Product Specifications
Certification
RUO
Reactivity
Human
Target Antigen
CD187
Clone
10D1-J16
Applications
FC (QC tested)
Format
FITC
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
*Doijen J, Van Loy T, De Haes W, Landuyt B, Luyten W, Schoofs L, Schols D: Signaling properties of the human chemokine receptors CXCR4 and CXCR7 by cellular electric impedance measurements. PLoS One. 2017 Sep 25;12 (9) :e0185354., URL: https://pubmed.ncbi.nlm.nih.gov/28945785/, *Espinoza-Sánchez NA, Vadillo E, Balandrán JC, Monroy-García A, Pelayo R, Fuentes-Pananá EM: Evidence of lateral transmission of aggressive features between different types of breast cancer cells. Int J Oncol. 2017 Nov;51 (5) :1482-1496., URL: https://pubmed.ncbi.nlm.nih.gov/29048610/, *Guan L, Li X, Wei J, Liang Z, Yang J, Weng X, Wu X: Antigen-specific CD8+ memory stem T cells generated from human peripheral blood effectively eradicate allogeneic targets in mice. Stem Cell Res Ther. 2018 Dec 7;9 (1) :337., URL: https://pubmed.ncbi.nlm.nih.gov/30526661/
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The mouse monoclonal antibody 10D1-J16 recognizes an extracellular epitope on CD187/CXCR7, a transmembrane protein of chemokine receptor family.
Applications Notes
6
Isotype
Mouse IgG2a kappa
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