BTK-IN-38
BTK-IN-38 (Example 125) is a potent BTK inhibitor. BTK-IN-38 inhibits DOHH2 and BT474 cells proliferation with IC50s of 114 and 340 nM, respectively[1].
Product Specifications
CAS Number
2758410-51-2
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btk-in-38.html
Smiles
FC(C1=CC=CC=C1)(C2=CC=C(C3=C4C(N)=NC=CN4C(C56COC(CC5)(CC6)CO)=N3)C=C2)F
Molecular Formula
C27H26F2N4O2
Molecular Weight
476.52
References & Citations
[1]Chunchao Yue, et al. Compound serving as btk inhibitor, preparation method therefor, and use thereof. China, WO2022012510. 2022-01-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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