Ethyl LipotF
Ethyl LipotF is a selective FTO inhibitor that significant increases modified N6-methyladenosine (m6A) levels in HeLa cells in a concentration-dependent manner[1].
Product Specifications
CAS Number
1808089-27-1
UNSPSC
12352005
Target
Fat Mass and Obesity-associated Protein (FTO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ethyl-lipotf.html
Purity
99.25
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCOC(/C=C/C(NNC(C1=CN=CC=C1CC2=CC=CC=C2)=O)=O)=O
Molecular Formula
C19H19N3O4
Molecular Weight
353.37
References & Citations
[1]Toh JDW, et al. A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTO. Chem Sci. 2015 Jan 1;6 (1) :112-122.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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