Ethyl LipotF

Ethyl LipotF is a selective FTO inhibitor that significant increases modified N6-methyladenosine (m6A) levels in HeLa cells in a concentration-dependent manner[1].

Product Specifications

CAS Number

[1808089-27-1]

UNSPSC

12352005

Target

Fat Mass and Obesity-associated Protein (FTO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ethyl-lipotf.html

Purity

99.25

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCOC(/C=C/C(NNC(C1=CN=CC=C1CC2=CC=CC=C2)=O)=O)=O

Molecular Formula

C19H19N3O4

Molecular Weight

353.37

References & Citations

[1]Toh JDW, et al. A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTO. Chem Sci. 2015 Jan 1;6 (1) :112-122.