WNK3 Polyclonal Antibody

Rabbit Anti-WNK3 Polyclonal Antibody

Product Specifications

Background

WNK3 (WNK Lysine Deficient Protein Kinase 3) encodes a protein belonging to the ‘with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Serine/threonine-protein kinase WNK3; Protein kinase lysine-deficient 3; Protein kinase with no lysine 3

Gene ID

65267

Accession Number

Q9BYP7

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human WNK3 protein

Clonality

Polyclonal

Tag

WNK3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

198kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of WNK3 protein

Observed Molecular Weight

198

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000