Anti-Human/Rat/Fish AChR Antibody (Mab35)
Anti-Human/Rat/Fish AChR Antibody (Mab35) is an anti-human/rat/fish AChR IgG1 monoclonal antibody. Anti-Human/Rat/Fish AChR Antibody (Mab35) can attack the AChR of neuromuscular junctions. Anti-Human/Rat/Fish AChR Antibody (Mab35) can be used for the construction of myasthenia gravis models[1][2][3].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352203
Target
NAChR
Type
Inhibitory Antibodies
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/anti-human-rat-fish-achr-antibody-mab35.html
Purity
95.00
Solubility
10 mM in DMSO
Smiles
[Anti-Human/Rat/FishAChRAntibody(Mab35)]
Molecular Weight
(150 kDa)
References & Citations
[1]Kuboi Y, et al. Identification of potent siRNA targeting complement C5 and its robust activity in pre-clinical models of myasthenia gravis and collagen-induced arthritis. Mol Ther Nucleic Acids. 2023 Jan 13;31:339-351.|[2]Gu H, et al. Characterization and localization of adrenal nicotinic acetylcholine receptors: evidence that mAb35-nicotinic receptors are the principal receptors mediating adrenal catecholamine secretion. J Neurochem. 1996 Apr;66 (4) :1454-61.|[3]Jin L, et al. Nicotinic receptor alpha subunits in magnocellular neurons of rat hypothalamus. Neuroreport. 2004 Oct 25;15 (15) :2333-6.
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4°C for 2 years, do not freeze
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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