UBQL2 Polyclonal Antibody

UBQLN2 (Ubiquilin 2) is a Protein Coding gene. Diseases associated with UBQLN2 include Amyotrophic Lateral Sclerosis 15, With Or Without Frontotemporal Dementia and Ubqln2-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia. Among its related pathways are Protein processing in endoplasmic reticulum and Clathrin-mediated endocytosis. UBQLN2 encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein.

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000