UBP35 Polyclonal Antibody

Rabbit Anti-UBP35 Polyclonal Antibody

Product Specifications

Background

USP35 (Ubiquitin Specific Peptidase 35) is a Protein Coding gene. Among its related pathways are Ubiquitin-Proteasome Dependent Proteolysis. USP35 encodes a member of the peptidase C19 family of ubiquitin-specific proteases. These deubiquitinating enzymes (DUBs) catalyze the removal of ubiquitin proteins from other proteins. The encoded protein associates with polarized mitochondria and has been shown to inhibit NF-kappa B activation and delay PARK2-mediated degradation of mitochondria. Expression of USP35 is upregulated by the let-7a microRNA and reduced expression has been observed in human tumor tissues.

CAS Number

9007-83-4

Product Name Alternative

Ubiquitin carboxyl-terminal hydrolase 35; Deubiquitinating enzyme 35; Ubiquitin thioesterase 35; Ubiquitin-specific-processing protease 35

Gene ID

57558

Accession Number

Q9P2H5

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human UBP35 protein

Clonality

Polyclonal

Tag

UBP35

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

111kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of UBP35 protein

Observed Molecular Weight

111

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000