TSHR Polyclonal Antibody

Rabbit Anti-TSHR Polyclonal Antibody

Product Specifications

Background

Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed: 11847099, PubMed: 12045258) . Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2: GPHB5) or thyrostimulin (PubMed: 12045258) . The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed: 11847099) . Plays a central role in controlling thyroid cell metabolism (By similarity) .

CAS Number

9007-83-4

Product Name Alternative

Thyrotropin receptor; Thyroid-stimulating hormone receptor; TSH-R

Gene ID

7253

Accession Number

P16473

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human TSHR protein at amino acid sequence of 280-360

Clonality

Polyclonal

Tag

TSHR

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

84kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of TSHR protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000