TNPO1 Polyclonal Antibody

TNPO1 (Transportin 1) is a Protein Coding gene. Diseases associated with TNPO1 include Hiv-1 and Dementia, Frontotemporal. Among its related pathways are Development_TGF-beta receptor signaling and CDK-mediated phosphorylation and removal of Cdc6. TNPO1 encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of TNPO1 results in two transcript variants encoding different proteins.

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000