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SYT14 Polyclonal Antibody

Rabbit Anti-SYT14 Polyclonal Antibody

Product Specifications

Background

SYT14 (Synaptotagmin 14) is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmin. Mutations in SYT14 are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11), and a t (1;3) translocation of this gene has been associated with neurodevelopmental abnormalities. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of SYT14 is located on the long arm of chromosome 4.

CAS Number

9007-83-4

Product Name Alternative

Synaptotagmin-14; Synaptotagmin XIV; SytXIV

Gene ID

255928

Accession Number

Q8NB59

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human SYT14 protein

Clonality

Polyclonal

Tag

SYT14

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

61kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of SYT14 protein

Observed Molecular Weight

61

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Synaptotagmin-14; Synaptotagmin XIV; SytXIV

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q8NB59

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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