SPRE1 Polyclonal Antibody

Rabbit Anti-SPRE1 Polyclonal Antibody

Product Specifications

Background

The protein encoded by SPRED1 is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in SPRED1 are a cause of neurofibromatosis type 1-like syndrome (NFLS) .

CAS Number

9007-83-4

Product Name Alternative

Sprouty-related; EVH1 domain-containing protein 1; Spred-1; hSpred1

Gene ID

161742

Accession Number

Q7Z699

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human SPRE1 protein at amino acid sequence of 210-290

Clonality

Polyclonal

Tag

SPRE1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

48kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of SPRE1 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000