SKI Polyclonal Antibody

Rabbit Anti-SKI Polyclonal Antibody

Product Specifications

Background

SKI encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling and may play a role in neural tube development and muscle differentiation. SKI (SKI Proto-Oncogene) is a Protein Coding gene. Diseases associated with SKI include Shprintzen-Goldberg Syndrome and Goldberg-Shprintzen Megacolon Syndrome. Among its related pathways are SMAD Signaling Network and Development_TGF-beta receptor signaling.

CAS Number

9007-83-4

Product Name Alternative

Ski oncogene; Proto-oncogene c-Ski

Gene ID

6497

Accession Number

P12755

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human SKI protein

Clonality

Polyclonal

Tag

SKI

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

80kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of SKI protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000