SF3A3 Polyclonal Antibody

Rabbit Anti-SF3A3 Polyclonal Antibody

Product Specifications

Background

SF3A3 (Splicing Factor 3a Subunit 3) encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. SF3A3 has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Splicing factor 3A subunit 3; SF3a60; Spliceosome-associated protein 61; SAP 61

Gene ID

10946

Accession Number

Q12874

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human SF3A3 protein

Clonality

Polyclonal

Tag

SF3A3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

55kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of SF3A3 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000