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SEC62 Polyclonal Antibody

Rabbit Anti-SEC62 Polyclonal Antibody

Product Specifications

Background

SEC62 (SEC62 Homolog, Preprotein Translocation Factor) is a Protein Coding gene. Among its related pathways are Protein processing in endoplasmic reticulum and Unfolded Protein Response (UPR) . The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by SEC62 and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

CAS Number

9007-83-4

Product Name Alternative

Translocation protein SEC62; Translocation protein 1; TP-1; hTP-1

Gene ID

7095

Accession Number

Q99442

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human SEC62 protein

Clonality

Polyclonal

Tag

SEC62

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

51kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of SEC62 protein

Product Datasheet

https://www.abbkine.com/datasheet/ABP60356.pdf

Observed Molecular Weight

43

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Translocation protein SEC62; Translocation protein 1; TP-1; hTP-1

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q99442

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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