RPB7 Polyclonal Antibody

Rabbit Anti-RPB7 Polyclonal Antibody

Product Specifications

Background

POLR2G encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation. POLR2G (RNA Polymerase II Subunit G) is a Protein Coding gene. Diseases associated with POLR2G include Myasthenic Syndrome, Congenital, 5 and Congenital Myasthenic Syndrome. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and DNA damage_Role of Brca1 and Brca2 in DNA repair.

CAS Number

9007-83-4

Product Name Alternative

DNA-directed RNA polymerase II subunit RPB7; DNA-directed RNA polymerase II subunit G; RNA polymerase II 19 kDa subunit

Gene ID

5436

Accession Number

P62487

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human RPB7 protein

Clonality

Polyclonal

Tag

RPB7

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

18kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of RPB7 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000