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RHCE Polyclonal Antibody

Rabbit Anti-RHCE Polyclonal Antibody

Product Specifications

Background

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in RHCE results in amorph-type Rh- disease. Alternative splicing of RHCE results in multiple transcript variants encoding several different isoforms.

CAS Number

9007-83-4

Product Name Alternative

Blood group Rh (CE) polypeptide; Rh polypeptide 1; RhPI; Rh30A; RhIXB; Rhesus C/E antigens; CD_antigen: CD240CE

Gene ID

6006

Accession Number

P18577

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human RHCE protein at amino acid sequence of 161-210

Clonality

Polyclonal

Tag

RHCE

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

45kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of RHCE protein

Observed Molecular Weight

45

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Blood group Rh (CE) polypeptide; Rh polypeptide 1; RhPI; Rh30A; RhIXB; Rhesus C/E antigens; CD_antigen: CD240CE

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P18577

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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