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RGS20 Polyclonal Antibody

Rabbit Anti-RGS20 Polyclonal Antibody

Product Specifications

Background

The protein encoded by RGS20 (Regulator Of G Protein Signaling 20) belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G (z) -alpha and G (alpha) -i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for RGS20.

Product Name Alternative

Regulator of G-protein signaling 20; RGS20; Gz-selective GTPase-activating protein; Gz-GAP; Regulator of G-protein signaling Z1; Regulator of Gz-selective protein signaling 1

Gene ID

8601

Accession Number

O76081

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human RGS20 protein at amino acid sequence of 180-260

Clonality

Polyclonal

Tag

RGS20

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

42kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of RGS20 protein

Product Datasheet

https://www.abbkine.com/datasheet/ABP60155.pdf

Observed Molecular Weight

42

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Regulator of G-protein signaling 20; RGS20; Gz-selective GTPase-activating protein; Gz-GAP; Regulator of G-protein signaling Z1; Regulator of Gz-selective protein signaling 1

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/O76081

CAS Number

9007-83-4

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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