RECQ4 Polyclonal Antibody

Rabbit Anti-RECQ4 Polyclonal Antibody

Product Specifications

Background

The protein encoded by RECQL4 is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. RECQL4 is predominantly expressed in thymus and testis. Mutations in RECQL4 are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes.

CAS Number

9007-83-4

Product Name Alternative

ATP-dependent DNA helicase Q4; DNA helicase, RecQ-like type 4; RecQ4; RTS; RecQ protein-like 4

Gene ID

9401

Accession Number

O94761

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human RECQ4 protein at amino acid sequence of 1030-1110

Clonality

Polyclonal

Tag

RECQ4

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

132kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of RECQ4 protein

Observed Molecular Weight

132

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000