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RAPH1 Polyclonal Antibody

Rabbit Anti-RAPH1 Polyclonal Antibody

Product Specifications

Background

RAPH1 (Ras Association (RalGDS/AF-6) And Pleckstrin Homology Domains 1) is a Protein Coding gene. Among its related pathways are Cytoskeletal Signaling. RAPH1 encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by RAPH1 regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Ras-associated and pleckstrin homology domains-containing protein 1; RAPH1; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein; Lamellipodin; Proline-rich EVH1 ligand 2; PREL-2; Protein RMO1

Gene ID

65059

Accession Number

Q70E73

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human RAPH1 protein at amino acid sequence of 370-450

Clonality

Polyclonal

Tag

RAPH1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

137kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of RAPH1 protein

Product Datasheet

https://www.abbkine.com/datasheet/ABP60091.pdf

Observed Molecular Weight

137

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Ras-associated and pleckstrin homology domains-containing protein 1; RAPH1; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein; Lamellipodin; Proline-rich EVH1 ligand 2; PREL-2; Protein RMO1

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q70E73

Isotype

Rabbit IgG

Available Sizes

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