RAC2 Polyclonal Antibody

Rabbit Anti-RAC2 Polyclonal Antibody

Product Specifications

Background

RAC2 (Rac Family Small GTPase 2) encodes a member of the Ras superfamily of small guanosine triphosphate (GTP) -metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in RAC2 are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for RAC2 on chromosome 6.

CAS Number

9007-83-4

Product Name Alternative

Ras-related C3 botulinum toxin substrate 2; GX; Small G protein; p21-Rac2

Gene ID

5880

Accession Number

P15153

Reactivity

Human, Mouse, Bovine, Bovine

Immunogen

Synthesized peptide derived from part region of human RAC2 protein at amino acid sequence of 130-210

Clonality

Polyclonal

Tag

RAC2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

21kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of RAC2 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000