PURA Polyclonal Antibody

Rabbit Anti-PURA Polyclonal Antibody

Product Specifications

Background

PURA (Purine Rich Element Binding Protein A) product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of PURA has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

CAS Number

9007-83-4

Product Name Alternative

Transcriptional activator protein Pur-alpha; Purine-rich single-stranded DNA-binding protein alpha

Gene ID

5813

Accession Number

Q00577

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human PURA protein

Clonality

Polyclonal

Tag

PURA

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

35kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of PURA protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000