PTN2 Polyclonal Antibody

PTPN2 (Protein Tyrosine Phosphatase, Non-Receptor Type 2) is a Protein Coding gene. Diseases associated with PTPN2 include Rheumatoid Factor-Negative Juvenile Idiopathic Arthritis and Oligoarticular Juvenile Idiopathic Arthritis. Among its related pathways are Listeria monocytogenes entry into host cells and Jak-STAT signaling pathway (KEGG) . The protein encoded by PTPN2 is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of PTPN2, which suggested the roles in growth factor mediated cell signaling.

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000