PPME1 Polyclonal Antibody

Rabbit Anti-PPME1 Polyclonal Antibody

Product Specifications

Background

PPME1 (Protein Phosphatase Methylesterase 1) is a Protein Coding gene. Diseases associated with PPME1 include Malignant Glioma. PPME1 encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Protein phosphatase methylesterase 1; PME-1

Gene ID

51400

Accession Number

Q9Y570

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human PPME1 protein at amino acid sequence of 220-300

Clonality

Polyclonal

Tag

PPME1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

42kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of PPME1 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000