PDE5A Polyclonal Antibody
Rabbit Anti-PDE5A Polyclonal Antibody
Product Specifications
Background
PDE5A (Phosphodiesterase 5A) is a Protein Coding gene. Diseases associated with PDE5A include Priapism and Nonarteritic Anterior Ischemic Optic Neuropathy. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Platelet homeostasis. PDE5A encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of PDE5A results in three transcript variants encoding distinct isoforms.
CAS Number
9007-83-4
Product Name Alternative
CGMP-specific 3',5'-cyclic phosphodiesterase; cGMP-binding cGMP-specific phosphodiesterase; CGB-PDE
Gene ID
8654
Accession Number
O76074
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human PDE5A protein
Clonality
Polyclonal
Tag
PDE5A
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
96kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PDE5A protein
Observed Molecular Weight
96
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
CGMP-specific 3',5'-cyclic phosphodiesterase; cGMP-binding cGMP-specific phosphodiesterase; CGB-PDE
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O76074
Isotype
Rabbit IgG
Available Sizes
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