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2'-Deoxyinosine

2’-deoxyadenosine inhibits the growth of human colon-carcinoma cell lines and is found to be associated with purine nucleoside phosphorylase (PNP) deficiency.

Product Specifications

CAS Number

890-38-0

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/9-__2R,4S,5R_-4-Hydroxy-5-_hydroxymethyl_tetrahydrofuran-2-yl_-9H-purin-6-ol.html

Concentration

10mM

Purity

99.91

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[C@H]1C[C@H](N2C(N=CN=C3O)=C3N=C2)O[C@@H]1CO

Molecular Formula

C10H12N4O4

Molecular Weight

252.23

Precautions

H302, H315, H319, H335

References & Citations

[1]Bemi V, et al. Deoxyadenosine metabolism in a human colon-carcinoma cell line (LoVo) in relation to its cytotoxic effect in combination with deoxycoformycin. Int J Cancer. 1998 Mar 2;75 (5) :713-20.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Frequently Asked Questions

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