2'-Deoxyinosine
2’-deoxyadenosine inhibits the growth of human colon-carcinoma cell lines and is found to be associated with purine nucleoside phosphorylase (PNP) deficiency.
Product Specifications
CAS Number
[890-38-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/9-__2R,4S,5R_-4-Hydroxy-5-_hydroxymethyl_tetrahydrofuran-2-yl_-9H-purin-6-ol.html
Concentration
10mM
Purity
99.91
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@H]1C[C@H](N2C(N=CN=C3O)=C3N=C2)O[C@@H]1CO
Molecular Formula
C10H12N4O4
Molecular Weight
252.23
Precautions
H302, H315, H319, H335
References & Citations
[1]Bemi V, et al. Deoxyadenosine metabolism in a human colon-carcinoma cell line (LoVo) in relation to its cytotoxic effect in combination with deoxycoformycin. Int J Cancer. 1998 Mar 2;75 (5) :713-20.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Curated Selection
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