OSTCN Polyclonal Antibody

Rabbit Anti-OSTCN Polyclonal Antibody

Product Specifications

Background

BGLAP encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. Bone Gamma-Carboxyglutamate Protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

CAS Number

9007-83-4

Product Name Alternative

Osteocalcin; Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein

Gene ID

632

Accession Number

P02818

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human OSTCN protein

Clonality

Polyclonal

Tag

OSTCN

Applications

WB IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

11kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of OSTCN protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IF 1:100-300; ELISA 1:5000-20000; Not yet tested in other applications.