3α,7α-Dihydroxycoprostanic acid-d5

3α,7α-Dihydroxycoprostanic acid-d5 is deuterium labeled 3α,7α-Dihydroxycoprostanic acid. 3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid[1][1][2].

Product Specifications

UNSPSC

12352211

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

[2H]C([2H])([2H])C(C(O)=O)C([2H])([2H])CC[C@](C)([H])[C@](CC1)([H])[C@]2(C)[C@]1([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC2

Molecular Formula

C27H41D5O4

Molecular Weight

439.68

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]L Monnens, et al. Disturbances in bile acid metabolism of infants with the Zellweger (cerebro-hepato-renal) syndrome. Eur J Pediatr. 1980;133 (1) :31-5.