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Biotinylated Human Catenin beta-1 Protein, His, Avitag™ (MALS verified)

Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental cancer models of animals. The nuclear accumulation of β-catenin has been shown to be positively correlated with poor clinical outcomes, such as cancer progression, invasion, metastasis, and recurrence, resulting in low survival rates.

Product Specifications

Background

Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental cancer models of animals. The nuclear accumulation of β-catenin has been shown to be positively correlated with poor clinical outcomes, such as cancer progression, invasion, metastasis, and recurrence, resulting in low survival rates.

Specifications

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 63.8 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) .

Accession Number

P35222-1

Expression Region

Asn 138 - Glu 686

Host

E. coli

Target

Catenin beta-1

Conjugation

Biotin-labeled

Tag

C-10xHis & C-Avi

Source

Human

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Human LEF1 at 5 μg/mL (100 μL/well) can bind Biotinylated Human Catenin beta-1, His,Avitag (Cat. No. CA1-H81E3) with a linear range of 0.2-16 ng/mL (QC tested).

Format

Liquid

Buffer

0.1 M Sodium citrate, 150 mM NaCl, pH5.5

Additives

Glycerol

Molecular Weight

63.8 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

25ug*1

Host or Source

E. coli

Species

Human

Protein ID

P35222-1

Preservative

Glycerol

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