NUFP1 Polyclonal Antibody

Rabbit Anti-NUFP1 Polyclonal Antibody

Product Specifications

Background

NUFIP1 (NUFIP1, FMR1 Interacting Protein 1) encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of NUFIP1 resides on chromosome 6q12.

CAS Number

9007-83-4

Product Name Alternative

Nuclear fragile X mental retardation-interacting protein 1; Nuclear FMRP-interacting protein 1

Gene ID

26747

Accession Number

Q9UHK0

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human NUFP1 protein at amino acid sequence of 180-260

Clonality

Polyclonal

Tag

NUFP1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

54kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of NUFP1 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000