NUDC3 Polyclonal Antibody

Rabbit Anti-NUDC3 Polyclonal Antibody

Product Specifications

Background

The product of NUDCD3 (NudC Domain Containing 3) functions to maintain the stability of dynein intermediate chain. Depletion of NUDCD3 product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition.

CAS Number

9007-83-4

Product Name Alternative

NudC domain-containing protein 3

Gene ID

23386

Accession Number

Q8IVD9

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human NUDC3 protein at amino acid sequence of 30-110

Clonality

Polyclonal

Tag

NUDC3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

39kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of NUDC3 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000