NUAK2 Polyclonal Antibody

Rabbit Anti-NUAK2 Polyclonal Antibody

Product Specifications

Background

NUAK2 (NUAK Family Kinase 2) is a Protein Coding gene. Among its related pathways are Cytoskeletal Signaling and Glucose / Energy Metabolism. Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate Ser-464 of LATS1.

CAS Number

9007-83-4

Product Name Alternative

NUAK family SNF1-like kinase 2; Omphalocele kinase 2; SNF1/AMP kinase-related kinase; SNARK

Gene ID

81788

Accession Number

Q9H093

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human NUAK2 protein

Clonality

Polyclonal

Tag

NUAK2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

69kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of NUAK2 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000